<Back>

Fluid bed rotor process by principle is essentially a horizontal wurster process, because it fully utilizes the 3 main features below.

• Concurrent spraying takes place below the product bed without premature droplet evaporation.
• High centrifugal energy is created inside the product bed by the rotating disc. The process air which enters the process chamber vertically at the periphery of the rotating disc reinforces the product's helical motion, so that practically every particle is permanently rolling around its own axis.
• Regular, statistical reproducible exposure of the particles to the spray nozzle by means of a defined disc rotation speed.

Analysis have shown that the rotor induced centrifugal forces move the entire product bed creating a denser film deposition. i.e. To obtain a wurster identical drug release profile, one would have to apply a little less coating agent with the rotor.

Our Rotor is not limited to film coating only, but permits a number of processing options. Rotor granulation can be accomplished by spraying a suitable binder suspension on powders. Both granulate production and spher'oidization is completed by the spherical rope motion of the formulation. The final stage drying can be rapidly achieved as the large free area around the rotor disc allows the throughput of large air volumes.

Pellet ization, such as the production of non-pareils, is accomplished by rapid powder and binder addition onto dummy seals through a single, combined bottom spray nozzle (in this case tangential spray). This process allows weight gain of approximately 250% per hour.

<Back>